Acyclovir Sodium Injection 1000 mg/20 ml is a sterile intravenous formulation of Acyclovir, a potent antiviral medication used to treat severe herpes infections in immunocompromised or hospitalized patients. It targets DNA synthesis in herpes viruses, helping to reduce the severity, spread, and duration of infection.

• Powerful IV antiviral therapy for critical or systemic herpes infections

• Effective against Herpes Simplex Virus (HSV) and Varicella Zoster Virus (VZV)

• Preferred for patients unable to take oral medication or with disseminated infections

• Rapid onset of action via intravenous route

• Useful in immunocompromised patients, including those undergoing chemotherapy or organ transplants

• Herpes Simplex Encephalitis

• Severe initial or recurrent genital herpes

• Varicella-Zoster Virus infections (e.g., herpes zoster in immunocompromised individuals)

• HSV infections in neonates

• Prophylaxis in patients undergoing bone marrow or organ transplantation

• Administered intravenously over at least one hour

• Dosage depends on body weight, renal function, and indication

• Must be diluted and infused slowly to prevent renal complications

• Use under strict medical supervision in a hospital setting

• Use caution in patients with renal impairment – dosage adjustments required

• Monitor renal function and hydration status throughout treatment

• Not for intramuscular or subcutaneous injection

• Use reconstituted solution immediately or store under proper conditions if delayed

• Pregnant or breastfeeding women should use only if clearly needed

Common side effects:

• Nausea, vomiting

• Headache

• Local irritation at the injection site

Serious adverse reactions (less common):

• Nephrotoxicity (especially with rapid infusion or dehydration)

• Neurological effects: confusion, hallucinations, seizures (rare, in high doses or renal impairment)

• Hematologic effects: neutropenia or anemia

• Store below 25°C

• Protect from light and do not freeze

• Reconstituted solution should be used within specified time as per manufacturer guidelines

• Keep out of reach of children

Q1: Can this injection be given at home?
No. It should only be administered in a clinical or hospital setting by qualified healthcare professionals.

Q2: How long does a typical course last?
The duration depends on the type and severity of the infection, generally ranging from 5 to 21 days.

Q3: Is this injection effective for chickenpox?
Yes, especially for complicated or disseminated cases in adults or immunocompromised patients.