Aprecap (Aprepitant) 125 mg/80 mg is an antiemetic medication used to prevent nausea and vomiting caused by chemotherapy. It belongs to a class of drugs known as neurokinin-1 (NK1) receptor antagonists and works by blocking the action of substances in the brain that trigger nausea and vomiting. It is typically used in combination with other antiemetics such as corticosteroids and 5-HT3 antagonists.

• Prevents acute and delayed nausea and vomiting associated with highly emetogenic chemotherapy

• Enhances the effectiveness of standard antiemetic therapy

• Well-tolerated and easy-to-follow dosing schedule

• Reduces need for rescue antiemetics

• Improves patient comfort and treatment compliance during chemotherapy

Aprecap is usually given as a 3-day oral regimen:

• Day 1: Take one capsule of 125 mg one hour before chemotherapy

• Days 2 and 3: Take one capsule of 80 mg each morning
  Swallow the capsules whole with water, with or without food. Follow your doctor’s instructions closely.

• Typical regimen is 125 mg on Day 1, followed by 80 mg on Days 2 and 3

• Used in combination with other antiemetics for best results

• Do not exceed recommended dose or alter the schedule without consulting your doctor

• Not for use in children unless prescribed

• Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding

• Use with caution in patients with liver disease

• Aprepitant may interact with other medications including warfarin, hormonal contraceptives, and certain antifungals

• Always inform your healthcare provider of all medicines you are taking

• Common side effects include fatigue, dizziness, hiccups, constipation, and diarrhea. Rarely, allergic reactions such as rash, itching, or swelling may occur. Seek immediate medical attention for signs of serious reactions.

   

Store at room temperature below 25°C, in a dry place away from direct heat and moisture. Keep the medication out of reach of children.

Q1: What is Aprecap used for?
A1: Aprecap is used to prevent nausea and vomiting caused by chemotherapy, especially in highly emetogenic regimens.

Q2: Do I need to take Aprecap alone?
A2: No, Aprecap is typically used in combination with other antiemetics like dexamethasone and ondansetron.

Q3: Can I take Aprecap with food?
A3: Yes, Aprecap can be taken with or without food.

Q4: What if I miss a dose?
A4: If you miss a dose, take it as soon as possible unless it is almost time for the next dose. Do not double the dose.

Q5: Can Aprecap affect birth control pills?
A5: Yes, Aprecap may reduce the effectiveness of hormonal contraceptives. Use an alternative non-hormonal method during treatment and for one month afterward.