Celkeran (Chlorambucil) is an alkylating agent used in the treatment of cancers such as chronic lymphocytic leukemia (CLL), Hodgkin's lymphoma, and other malignancies. It works by interfering with the DNA in cancer cells, preventing them from multiplying. This oral medication is commonly prescribed for patients who may not respond well to other treatments. Chlorambucil has been a part of cancer treatment regimens for many years, offering a more manageable option for long-term therapy.

• Effective in treating CLL: Widely used for chronic lymphocytic leukemia and Hodgkin's lymphoma

• Convenient oral administration: Available in tablet form for easier daily use

• Improves quality of life: Used to manage cancer progression, allowing patients to live longer and more comfortable lives

• Used in combination therapy: Often paired with other medications to increase treatment efficacy

• Milder chemotherapy side effects: Compared to other chemotherapies, it has a relatively mild side effect profile

• Dosage: The typical starting dose is 5 mg per day, though dosage may vary based on individual needs and doctor recommendations

• Administration: Swallow the tablet whole with a full glass of water. Do not crush or chew the tablet

• Consistency: Take the medication consistently at the same time each day to ensure optimal results

• Missed Dose: If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. Do not take two doses at once to make up for a missed dose

• Course of Treatment: Treatment is typically cyclical, with breaks in between cycles, depending on the specific disease being treated

• Active Ingredient: Chlorambucil (5 mg per tablet)

• Recommended Dose: Start with 5 mg per day, as directed by your healthcare provider

• Administration: Oral (with water)

• Combination Therapy: Often combined with other medications to enhance the effectiveness of the treatment

• Blood Counts: Regular monitoring of blood counts is necessary due to the potential for bone marrow suppression

• Liver Function: Liver function may be affected. Routine liver function tests are recommended

• Pregnancy: Celkeran is contraindicated in pregnancy due to its potential to harm the fetus

• Breastfeeding: Should not be used while breastfeeding

• Drug Interactions: Inform your healthcare provider of all medications you are taking, including other chemotherapy drugs and medications that affect blood clotting

• Common: Fatigue, nausea, vomiting, hair loss, and loss of appetite

• Serious: Bone marrow suppression (low blood counts), liver toxicity, lung damage, and increased risk of infection

• Other: Rash, fever, or swelling of lymph nodes

• Seek medical help if you notice any unusual symptoms such as bleeding, bruising, or persistent fever

• Store at room temperature, between 20°C and 25°C

• Keep in a tightly closed container to protect from light and moisture

• Do not store in the bathroom or areas with high humidity

• Keep out of reach of children

• Dispose of unused medication according to local disposal guidelines

Q1. What is Celkeran used for?
A: Celkeran (Chlorambucil) is primarily used for the treatment of chronic lymphocytic leukemia (CLL), Hodgkin's lymphoma, and other cancers. It is also used to treat certain autoimmune diseases.

Q2. How should I take Celkeran?
A: Take one 5 mg tablet per day with a full glass of water. Do not crush or chew the tablet. Follow your healthcare provider's instructions regarding dosage and treatment duration.

Q3. What are the side effects of Celkeran?
A: Some common side effects include nausea, fatigue, and hair loss. Serious side effects may include bone marrow suppression, liver toxicity, and lung damage. Contact your doctor if you experience unusual symptoms.

Q4. Can Celkeran be taken during pregnancy?
A: Celkeran is contraindicated during pregnancy due to its potential to harm the unborn baby. It should only be used if absolutely necessary and under medical supervision.

Q5. How should I store Celkeran?
A: Store Celkeran at room temperature, away from light and moisture, in its original container. Keep out of reach of children.