Creon (Pancreatin) Capsules 300 mg are a pancreatic enzyme replacement therapy (PERT) designed to assist in the digestion of fats, proteins, and carbohydrates in individuals with exocrine pancreatic insufficiency (EPI). Each capsule contains a balanced mixture of digestive enzymes—lipase, amylase, and protease—to support normal digestion and nutrient absorption.

• Helps manage exocrine pancreatic insufficiency caused by conditions like chronic pancreatitis, cystic fibrosis, or pancreatic surgery

• Improves digestion and absorption of nutrients

• Reduces gastrointestinal discomfort such as bloating, flatulence, and fatty stools

• Enhances nutritional status and quality of life

• Convenient dosing with meals and snacks

Take Creon Capsules with meals and snacks, as directed by your doctor. Swallow the capsule whole with sufficient water. If necessary, the capsule may be opened, and the granules sprinkled on soft, acidic food (e.g., applesauce). Do not crush or chew the granules.

• Dosage is individualized based on the severity of enzyme deficiency and fat content in the diet

• Typically taken with every meal and snack

• Your doctor may adjust the dose based on symptom control and dietary intake

• Do not exceed the maximum daily enzyme units recommended

• Use under the supervision of a healthcare provider

• Not recommended for patients with hypersensitivity to pork proteins

• Long-term high doses may increase the risk of fibrosing colonopathy, particularly in children with cystic fibrosis

• Stay well hydrated during treatment

• Discuss all current medications and health conditions with your physician

• Possible side effects include abdominal pain, nausea, diarrhea, constipation, and flatulence. Rarely, high doses may cause hyperuricemia or allergic reactions. Contact your doctor if severe or persistent symptoms occur.

   

Store at temperatures below 25°C in a dry place, away from moisture and heat. Keep the container tightly closed. Do not refrigerate. Keep out of reach of children.

Q1: What is Creon 300 mg used for?
A1: Creon 300 mg is used to manage exocrine pancreatic insufficiency (EPI) by replacing digestive enzymes.

Q2: How should I take Creon 300 mg?
A2: Take Creon with meals or snacks, either swallowing the capsule whole or sprinkling the granules on soft acidic food without chewing.

Q3: Can Creon be used in children?
A3: Yes, but only under medical supervision with dosage carefully tailored to the child’s needs.

Q4: Is it safe for long-term use?
A4: Yes, Creon can be used long-term as prescribed, with regular monitoring to ensure effectiveness and safety.

Q5: What happens if I miss a dose?
A5: If you miss a dose, take it with your next meal or snack. Do not double the dose to make up for the missed one.