Creon (Pancreatin) Capsules 400 mg are pancreatic enzyme replacement therapy (PERT) used to support digestion in individuals with exocrine pancreatic insufficiency (EPI). Each capsule contains a mixture of natural enzymes—lipase, amylase, and protease—that help digest fats, carbohydrates, and proteins, respectively. Creon improves nutrient absorption and reduces gastrointestinal symptoms like bloating, gas, and steatorrhea.

• Restores digestive enzyme activity in patients with EPI

• Aids in proper digestion and nutrient absorption

• Reduces symptoms like gas, abdominal discomfort, and oily stools

• Improves nutritional status and overall well-being

• Suitable for conditions like chronic pancreatitis, cystic fibrosis, pancreatic cancer, or post-pancreatectomy

Take Creon capsules orally with meals and snacks, as prescribed. Swallow whole with water. Do not crush or chew the capsules or their contents, as this may damage the enzyme coating and reduce effectiveness.

• Dosage is individualized based on the fat content of meals and the patient’s clinical condition

• Typically taken with each meal and snack

• Dose adjustments should be made by the physician based on stool consistency and fat content

• Do not exceed the maximum recommended daily dose

• Use under medical supervision, especially in pediatric patients

• Prolonged high doses may cause fibrosing colonopathy, particularly in children with cystic fibrosis

• Not for use in patients with known allergies to pork proteins

• Inform your doctor of all existing health conditions before use

• Adequate hydration is important while taking enzyme supplements

• Common side effects may include abdominal pain, bloating, diarrhea, nausea, or constipation. High doses may lead to increased uric acid levels. Rarely, allergic reactions may occur. Report any persistent or severe symptoms to your doctor.

   

Store in a cool, dry place below 25°C. Keep the container tightly closed to protect from moisture. Do not refrigerate. Keep out of reach of children.

Q1: What is Creon 400 mg used for?
A1: Creon 400 mg is used to treat exocrine pancreatic insufficiency (EPI) by replacing digestive enzymes that the pancreas fails to produce.

Q2: When should I take Creon?
A2: Take Creon with meals and snacks, not on an empty stomach, to aid digestion.

Q3: Can I open the capsule?
A3: If swallowing is difficult, the capsule may be opened and the granules sprinkled on soft, acidic food. Do not chew the granules.

Q4: Is Creon safe for children?
A4: Yes, but only under strict medical supervision, as dosage must be carefully adjusted in children.

Q5: Does Creon cure pancreatic conditions?
A5: No, Creon does not cure the underlying cause but helps manage symptoms by aiding digestion.