Crizalk (Crizotinib) 250 mg Capsules

• Effective for ALK-positive NSCLC: Specifically targets lung cancers with ALK gene mutations

• Improved survival rates: Helps extend the lives of patients with ALK-positive lung cancer

• Convenient oral administration: Easy-to-take capsule form for daily use

• Fewer side effects compared to traditional chemotherapy: Targets specific cancer mechanisms to minimize damage to healthy cells

• Approved for use in both advanced and metastatic stages of cancer

• Dosage: The typical starting dose is 250 mg taken twice daily

• Administration: Swallow the capsules whole with a glass of water. Do not chew, crush, or open the capsule

• Consistency: Take the medication at the same times each day to help remember

• Missed Dose: If you miss a dose, take it as soon as possible unless it's almost time for your next dose. Do not take two doses at the same time to make up for a missed dose

• Treatment Duration: Follow your healthcare provider's instructions on the duration of treatment. Do not stop the medication without consulting your doctor

• Active Ingredient: Crizotinib (250 mg per capsule)

• Recommended Dose: 250 mg twice daily

• Route of Administration: Oral (with water)

• Monitoring: Regular monitoring is recommended to check for side effects and effectiveness

• Liver Function: Liver function tests are recommended, as Crizotinib can cause liver problems

• QT Interval: It can affect heart rhythms, so periodic ECGs (electrocardiograms) are recommended

• Eye Problems: Vision disturbances are a known side effect, and patients should have regular eye exams

• Pregnancy: Crizalk is contraindicated during pregnancy due to its potential to harm the fetus

• Drug Interactions: Inform your doctor of any other medications you are taking, especially those that affect heart rhythm or liver enzymes

• Common: Fatigue, diarrhea, nausea, vomiting, and vision disturbances

• Serious: Liver damage, QT prolongation, pneumonitis (lung inflammation), and heart problems

• Other: Peripheral edema (swelling of the extremities), loss of appetite, and muscle spasms

• Seek medical attention if you experience any severe reactions, such as severe dizziness, difficulty breathing, or yellowing of the skin or eyes

• Store Crizalk at room temperature, between 20°C and 25°C

• Keep the capsules in their original container, tightly closed to protect from moisture and light

• Do not store in the bathroom or areas with high humidity

• Keep out of reach of children

• Dispose of unused medication as per local guidelines

Q1. What is Crizalk used for?
A: Crizalk is used to treat non-small cell lung cancer (NSCLC) in patients with ALK gene mutations. It is effective in targeting and stopping the growth of cancer cells with this mutation.

Q2. How should I take Crizalk?
A: Take 250 mg capsules twice daily with a glass of water. Do not chew or crush the capsules. Try to take it at the same time every day to maintain consistency.

Q3. What are the side effects of Crizalk?
A: Some common side effects include fatigue, nausea, vomiting, and vision problems. Serious side effects may include liver damage or lung inflammation. Contact your healthcare provider if you experience any severe symptoms.

Q4. Can Crizalk be taken during pregnancy?
A: Crizalk is contraindicated during pregnancy due to the potential risks to the fetus. Always consult your healthcare provider before using any medication during pregnancy.

Q5. How should I store Crizalk?
A: Store Crizalk capsules at room temperature, away from moisture and heat. Keep out of reach of children.