Dacilon Injection contains Dactinomycin (Actinomycin D), a potent chemotherapy medication used to treat various types of cancer. It is primarily indicated in the treatment of Wilms' tumor, Ewing’s sarcoma, rhabdomyosarcoma, and gestational trophoblastic neoplasia. Dactinomycin works by binding to DNA and inhibiting RNA synthesis, which interferes with cancer cell growth and replication. It is administered intravenously and is often part of combination chemotherapy protocols.

• Effective Anticancer Agent: Used in several pediatric and adult cancers.

• Mechanism of Action: Interferes with cancer cell RNA production, stopping their growth.

• Combination Therapy: Often paired with other drugs to improve treatment outcomes.

• Trusted Chemotherapy Option: Part of established oncology treatment regimens.

• Administration: Administered via intravenous injection under the supervision of a qualified oncologist.

• Treatment Setting: Given in a hospital or clinical setting due to its cytotoxic nature.

• Medical Supervision: Regular monitoring is necessary during and after administration.

• Form: Injection

• Strength: 0.5 mg Dactinomycin per vial

• Route: Intravenous (IV) use only

• Dosage: Determined based on patient’s body surface area, type of cancer, and treatment regimen.

• Cycles: Administered in cycles, often in combination with other chemotherapeutic agents.

• Monitoring: Requires regular blood counts, renal, and hepatic function tests.

• Caution in Liver/Kidney Disease: Dose adjustment may be necessary.

• Pregnancy: Contraindicated during pregnancy due to potential fetal harm.

• Precautions: Avoid contact with skin or mucous membranes; Dactinomycin is highly toxic.

• Common Side Effects: Nausea, vomiting, mouth sores, diarrhea, and fatigue.

• Serious Effects: Bone marrow suppression, liver toxicity, infection, and tissue necrosis at injection site.

• Extravasation Risk: Severe tissue damage may occur if the drug leaks outside the vein.

• Immediate Attention: Required for signs of infection, bleeding, or severe allergic reactions.

• Store in a refrigerated environment (2–8°C).

• Protect from light and moisture.

• Keep the vial in its original packaging until ready for use.

• Follow institutional protocols for the safe disposal of cytotoxic agents.

Q1. What is Dacilon used for?
A: Dacilon is used in the treatment of cancers such as Wilms’ tumor, Ewing's sarcoma, rhabdomyosarcoma, and gestational trophoblastic tumors.

Q2. How is it administered?
A: It is given by intravenous injection, usually in a hospital setting under medical supervision.

Q3. Can Dacilon be used in children?
A: Yes, it is often used in pediatric oncology, especially for Wilms’ tumor and rhabdomyosarcoma.

Q4. Are there risks of side effects?
A: Yes. Common effects include nausea, vomiting, and fatigue, while serious effects can include bone marrow suppression and liver toxicity.

Q5. How should I handle the medication?
A: Only trained healthcare professionals should handle and administer Dacilon due to its highly toxic nature.