Fosolin Injection contains Fosphenytoin Sodium, a water-soluble prodrug of phenytoin, used for the treatment and prevention of seizures, particularly status epilepticus and during neurosurgery. It is administered intravenously or intramuscularly when oral administration is not feasible or rapid seizure control is required. Fosphenytoin converts to active phenytoin in the body, helping to stabilize neuronal membranes and suppress abnormal brain activity.

• Rapid control of seizures, especially in emergency settings

• Suitable for patients unable to take oral phenytoin

• Lower risk of local irritation compared to phenytoin injection

• Can be used prophylactically in neurosurgery

• Useful in managing status epilepticus and acute seizure episodes

Fosolin Injection is administered by a healthcare professional via intravenous (IV) or intramuscular (IM) route. Dosage is based on body weight and seizure severity. It is typically given in a clinical or hospital setting where the patient can be closely monitored.

• Common loading dose: 15 to 20 mg PE/kg IV at a rate not exceeding 150 mg PE/min

• Maintenance dose: 4 to 6 mg PE/kg/day in divided doses

• Dosage adjustments may be required based on serum phenytoin levels and renal function

• PE = Phenytoin sodium equivalent

• Not to be used interchangeably with oral phenytoin without dose adjustment

• Continuous cardiac and respiratory monitoring is required during IV administration

• Use with caution in patients with hypotension, heart conditions, or liver impairment

• Not recommended during pregnancy unless clearly necessary

• May interact with other CNS depressants and antiepileptic drugs

• Must not be mixed with certain IV solutions—use only as directed

Common side effects may include:

• Dizziness

• Drowsiness

• Nausea or vomiting

• Injection site reactions

• Tingling or itching sensations

Serious side effects:

• Hypotension

• Arrhythmias

• Severe allergic reactions (e.g., rash, fever, swelling)
  Seek immediate medical attention if any serious reactions occur.

Store Fosolin Injection between 2°C and 8°C. Do not freeze. Protect from light. Keep out of reach of children. Use within recommended time after opening.

Q1: What is Fosolin Injection used for?
A: It is used to control and prevent seizures, particularly in emergencies like status epilepticus or when oral phenytoin is not an option.

Q2: How fast does it work?
A: It begins converting to phenytoin shortly after administration and acts rapidly to stabilize seizures.

Q3: Can I use Fosolin at home?
A: No, it is for hospital or clinical use only under medical supervision.

Q4: Is Fosolin safer than phenytoin injection?
A: Fosolin generally causes less local irritation and is better tolerated when given intravenously.