Glycomet GP 500 mg/1 mg Tablet is a combination oral antidiabetic medication containing Metformin (500 mg) and Glimepiride (1 mg). It is commonly prescribed for managing type 2 diabetes mellitus in adults. The dual mechanism helps in both reducing hepatic glucose production and enhancing insulin secretion from the pancreas, leading to effective blood sugar control. This lower-dose variant is ideal for initiating therapy or for patients requiring mild glycemic correction.

• Dual-action formula for better glycemic control

• Supports insulin production and improves insulin sensitivity

• Lower Glimepiride dose reduces the risk of hypoglycemia

• Helps manage both fasting and postprandial blood glucose levels

• Useful in early-stage type 2 diabetes or when stepping down from higher doses

• Take one tablet daily, preferably with breakfast or the first major meal

• Swallow whole with water—do not chew or crush

• Maintain a consistent daily schedule for optimal results

• Follow your physician’s instructions regarding diet and exercise

• Usual starting dose: 500 mg/1 mg once daily

• Dose may be adjusted based on individual response and blood sugar levels

• Do not take more than the prescribed dose

• If a dose is missed, take it promptly unless it’s close to the next scheduled dose

• Not suitable for individuals with type 1 diabetes or severe kidney or liver disease

• May increase risk of hypoglycemia, especially if meals are delayed or missed

• Avoid alcohol, as it may amplify side effects like low blood sugar or lactic acidosis

• Inform your doctor about any pre-existing conditions or medications

• Regular monitoring of blood sugar and kidney function is advised

• Common:

• Mild stomach upset, bloating, or nausea (from Metformin)

• Dizziness or weakness due to low blood sugar

• Rare:

• Lactic acidosis (serious but rare with Metformin)

• Skin rash or allergic reaction

• Liver enzyme changes

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• Headache

• Store at a temperature below 30°C

• Keep away from moisture and direct heat

• Store in the original packaging

• Keep out of reach of children

Q1. Who is Glycomet GP 500/1 best suited for?
It is ideal for patients who are starting combination therapy or those needing a low-dose Glimepiride formulation.

Q2. Can it be taken on an empty stomach?
No, it should always be taken with food to prevent stomach upset and reduce the risk of hypoglycemia.

Q3. Will this medication cause weight gain?
Mild weight gain may occur due to Glimepiride. Regular physical activity can help manage weight.

Q4. Is this medicine safe for elderly patients?
Yes, but dose adjustment and close monitoring may be required, especially to avoid low blood sugar.