Lenalid 25 mg Tablets contain Lenalidomide, a derivative of thalidomide, used to treat certain cancers and blood disorders. It is an immunomodulatory and antiangiogenic agent prescribed mainly for multiple myeloma, myelodysplastic syndromes (MDS) with chromosome 5q deletion, and mantle cell lymphoma (MCL). Lenalid 25 mg is a potent formulation and is typically used in patients requiring a higher therapeutic dose or under close medical supervision as part of combination therapy.

• Effective in Multiple Myeloma: Improves survival rates, especially when used with dexamethasone.

• Treats MDS with 5q Deletion: Helps reduce transfusion dependence.

• Controls Lymphomas: Used in mantle cell lymphoma following at least one prior therapy.

• Modulates Immune System: Enhances immune response against cancer cells.

• Reduces Angiogenesis: Limits tumor blood supply, slowing cancer growth.

• Administration: Take the tablet orally with water.

• Timing: Generally once daily, at the same time each day.

• With/Without Food: Can be taken with or without meals.

• Swallow Whole: Do not crush, chew, or open the tablets.

• Strength: 25 mg Lenalidomide per tablet

• Typical Schedule:

  • Multiple Myeloma: Often taken for 21 days of a 28-day cycle along with dexamethasone.

  • MDS/MCL: Dosage and duration vary based on patient condition and physician assessment.

• Dose Adjustments: May be needed in renal impairment or based on blood count results.

• Missed Dose: Skip if it's almost time for the next dose. Do not double up.

• Pregnancy Risk: Highly teratogenic. Contraindicated in pregnancy. Use strict birth control.

• Routine Monitoring: Regular blood tests are essential to monitor WBC, platelets, and liver/kidney functions.

• Clotting Risk: Increased chance of DVT or pulmonary embolism.

• Infection Risk: Maintain hygiene and avoid exposure to infections.

• Avoid Donating Blood/Sperm: Not allowed during and shortly after treatment.

• Common:

• Tiredness

• Constipation/diarrhea

• Muscle cramps

• Skin rash

• Serious:

• Blood clots

• Severe allergic reactions

• Liver problems

• Secondary malignancies (rare)

• Tumor lysis syndrome

• Report any chest pain, swelling in the legs, unusual bleeding, or fever immediately.

• Dizziness

• Low blood cell counts (anemia, neutropenia, thrombocytopenia)

• Temperature: Store at 20°C to 25°C (68°F to 77°F).

• Dry Environment: Protect from moisture.

• Secure Storage: Keep out of reach of children.

• Original Packaging: Do not remove from the original container until use.

Q1. What conditions does Lenalid 25 mg treat?
A: It treats multiple myeloma, myelodysplastic syndromes with 5q deletion, and mantle cell lymphoma.

Q2. Can I take Lenalid 25 mg during pregnancy?
A: No. It is highly dangerous to an unborn baby. Effective contraception is mandatory during and after use.

Q3. How long can Lenalid 25 mg be used?
A: Duration depends on response and side effects. Treatment may continue in cycles under your doctor's supervision.

Q4. Are there any food restrictions while on Lenalid?
A: There are no specific food restrictions, but ensure consistent timing of doses.

Q5. Is it safe to travel while on Lenalid?
A: Generally yes, but avoid exposure to infections and maintain all scheduled lab tests and medication timings.