Lupride Depot 22.50 mg is a long-acting injectable formulation of Leuprolide Acetate, a gonadotropin-releasing hormone (GnRH) agonist. It is designed for 6-month (24-week) hormonal suppression therapy, commonly prescribed for advanced prostate cancer, endometriosis, uterine fibroids, and other hormone-sensitive conditions. It works by reducing gonadotropin secretion, leading to decreased levels of testosterone in men and estrogen in women.

• Provides 6-month hormonal suppression in a single dose

• Helps manage symptoms of prostate cancer, fibroids, and endometriosis

• Reduces frequency of injections, improving treatment adherence

• Effective in suppressing precocious puberty in children

• Minimizes hormone-driven tumor growth or flare-ups

• Administered as a single intramuscular (IM) injection every 24 weeks (6 months)

• Should be administered by a qualified healthcare provider

• Ensure proper reconstitution with the provided sterile diluent before injection

• Medical supervision is necessary during treatment for monitoring hormonal levels and side effects

• Active Ingredient: Leuprolide Acetate 22.50 mg

• Typical Use:

  • Prostate cancer: One injection every 24 weeks

  • Endometriosis/Fibroids: Dosage and duration based on physician's recommendation

• Pediatric Use: For central precocious puberty (CPP) under specific clinical protocols

• No dose adjustment usually needed unless advised by a healthcare provider

• Not to be used during pregnancy or lactation

• May initially cause a flare-up in hormone levels before suppression begins

• Use caution in patients with diabetes, cardiac issues, or osteoporosis

• Bone mineral density monitoring is recommended for long-term therapy

• Regular follow-ups are essential to assess treatment efficacy and side effects

• Common Side Effects:

• Hot flashes

• Injection site pain or swelling

• Headaches

• Mood changes

• Serious Side Effects:

• Osteoporosis with long-term use

• Depression or mood disorders

• Seizures (rare)

• Cardiovascular effects in predisposed individuals

• Seek immediate medical attention for symptoms like chest pain, vision changes, or severe allergic reaction.

• Decreased libido

• Store below 25°C

• Protect from light and moisture

• Reconstituted product should be used immediately

• Keep out of reach of children and pets

Q1. How often is Lupride Depot 22.50 mg administered?
A: Once every 6 months (24 weeks) via intramuscular injection.

Q2. Can it be self-administered?
A: No, it must be administered by a qualified medical professional.

Q3. What conditions does it treat?
A: Commonly used for advanced prostate cancer, endometriosis, uterine fibroids, and precocious puberty.

Q4. Are there long-term risks?
A: Bone thinning and mood changes may occur with long-term use. Regular monitoring is recommended.

Q5. What if I miss my injection schedule?
A: Contact your doctor as soon as possible to reschedule. Delays can reduce the treatment’s effectiveness.