Metformin 500 mg Tablets are an oral medication widely used to manage type 2 diabetes mellitus. As a member of the biguanide class, Metformin works by reducing glucose production in the liver, improving the body's response to insulin, and enhancing glucose uptake in muscle cells. This helps control blood sugar levels, reducing the risk of diabetes-related complications.

• Effectively lowers blood sugar levels

• Improves insulin sensitivity

• Reduces hepatic glucose output

• Supports blood glucose control alongside diet and exercise

• May promote modest weight loss or weight stabilization

• Low risk of causing hypoglycemia when used alone

• Take orally with meals to minimize gastrointestinal side effects

• Swallow the tablet whole with water

• Follow your healthcare provider’s instructions for dose and timing

• Regular blood glucose monitoring is important

• Typical starting dose: 500 mg once or twice daily

• Dose may be gradually increased based on blood sugar control and tolerance

• Maximum daily dose usually ranges between 2000 to 2500 mg depending on formulation and patient needs

• Extended-release tablets should not be crushed or chewed

• Not suitable for patients with severe kidney impairment or metabolic acidosis

• Use with caution in patients with liver disease or congestive heart failure

• Rare risk of lactic acidosis, a serious metabolic condition — seek immediate medical help if symptoms arise

• Avoid excessive alcohol intake during treatment

• Common side effects:

• Nausea

• Diarrhea

• Less common but serious effects:

• Lactic acidosis (rare)

• Vitamin B12 deficiency with long-term use

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• Abdominal pain or discomfort

• Loss of appetite

• Store at room temperature between 15°C to 30°C

• Protect from moisture, heat, and direct sunlight

• Keep tablets in original packaging until use

• Keep out of reach of children

Q1. Can I take Metformin 500 mg without food?
It is recommended to take it with meals to reduce stomach upset.

Q2. How long does it take to see the effect?
Blood sugar improvements may be noticed within days, but optimal effects develop over weeks.

Q3. What if I miss a dose?
Take the missed dose as soon as you remember unless it’s close to the next dose. Do not double the dose.

Q4. Does Metformin cause weight gain?
Metformin is usually weight-neutral or may cause slight weight loss.