Mounjaro (Tirzepatide) 12.5 mg Injection is a once-weekly subcutaneous medication designed to enhance blood sugar control in adults with type 2 diabetes mellitus. Tirzepatide acts as a dual GIP and GLP-1 receptor agonist, providing a unique mechanism that improves insulin sensitivity, reduces glucagon secretion, and slows gastric emptying. This formulation is typically used during the dose escalation phase or as a maintenance dose, depending on patient response.

• Dual incretin action for superior glycemic control

• Helps lower HbA1c and post-meal glucose levels

• Aids in healthy weight reduction in patients with type 2 diabetes

• Once-weekly dosing improves convenience and adherence

• Can be used as monotherapy or with other antidiabetic agents

• Administer once weekly, on the same day each week

• Inject subcutaneously into the abdomen, upper arm, or thigh

• Rotate injection sites weekly

• Use a new pen for each dose; follow the injection instructions provided by your healthcare provider

• The 12.5 mg dose is typically part of the titration schedule following lower doses (e.g., 10 mg)

• Not intended as a starting dose

• Dose should be adjusted based on clinical response and tolerability under medical supervision

• Continue with diet and exercise as prescribed

• Not recommended for individuals with type 1 diabetes or diabetic ketoacidosis

• Contraindicated in patients with a personal or family history of medullary thyroid carcinoma or MEN 2

• Use with caution in patients with severe gastrointestinal or kidney disorders

• Safety during pregnancy or breastfeeding has not been established

• Common side effects:

• Nausea

• Vomiting

• Serious side effects (rare):

• Acute pancreatitis

• Gallbladder problems

• Kidney issues related to dehydration

• Severe allergic or injection site reactions

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• Diarrhea

• Reduced appetite

• Indigestion or constipation

• Store in a refrigerator at 2°C to 8°C

• Do not freeze

• If necessary, may be stored at room temperature (up to 30°C) for a maximum of 21 days

• Keep in original packaging to protect from light

• Keep out of reach of children

Q1. What is the purpose of the 12.5 mg Mounjaro dose?
It is part of the dose escalation schedule to improve tolerability and optimize blood sugar control.

Q2. How should I take this injection?
Inject subcutaneously once weekly, on the same day each week, at any time of day.

Q3. What happens if I miss a dose?
If missed, take the dose within 4 days. If more than 4 days have passed, skip the dose and resume on your next scheduled day.

Q4. Can I take Mounjaro with other diabetes medications?
Yes, but always consult your healthcare provider to avoid interactions or low blood sugar.