Mounjaro (Tirzepatide) 2.5 mg Injection is a once-weekly injectable medication used for the treatment of type 2 diabetes mellitus in adults. Tirzepatide is a dual GIP and GLP-1 receptor agonist that helps improve blood sugar control by enhancing insulin secretion, suppressing glucagon, and delaying gastric emptying. The 2.5 mg dose is typically the starting dose in a titration regimen to minimize gastrointestinal side effects and allow the body to adjust before increasing to higher doses.

• Initiates glucose-lowering treatment with minimal side effects

• Helps improve fasting and postprandial blood sugar levels

• Supports healthy weight loss

• Once-weekly dosing for convenience

• Enables smooth transition to higher maintenance doses

• Inject once every week, on the same day each week

• Administer subcutaneously in the abdomen, upper arm, or thigh

• Use a new prefilled pen for each injection

• Change injection site with each use to avoid skin irritation

• 2.5 mg is the recommended starting dose

• Typically taken for 4 weeks before increasing to 5 mg or higher, depending on tolerance and glycemic response

• Always follow your healthcare provider’s instructions for dose adjustments

• Should be used in combination with diet and exercise

• Not suitable for type 1 diabetes or diabetic ketoacidosis

• Contraindicated in patients with a history of medullary thyroid carcinoma or MEN 2

• Use cautiously in those with gastrointestinal disorders or kidney impairment

• Avoid during pregnancy and breastfeeding unless directed by a healthcare provider

• Common side effects:

• Mild nausea

• Vomiting

• Serious side effects (less common):

• Pancreatitis

• Allergic reactions

• Kidney problems due to dehydration

• Gallbladder issues

•  

• Diarrhea

• Decreased appetite

• Constipation

• Store in a refrigerator at 2°C to 8°C

• Do not freeze

• Can be stored at room temperature (up to 30°C) for up to 21 days

• Keep in original packaging to protect from light

• Store out of reach of children

Q1. Is 2.5 mg the standard treatment dose?
No, 2.5 mg is the starting dose used to initiate therapy and is not intended as the long-term maintenance dose.

Q2. Can I stay on 2.5 mg if I tolerate it well?
While tolerated, most patients will need a higher dose (such as 5 mg or more) to achieve optimal glucose control.

Q3. What if I miss my weekly injection?
You can take the missed dose within 4 days. If more than 4 days have passed, skip it and take the next dose as scheduled.

Q4. Does this dose help with weight loss?
Yes, even the starting dose may support appetite control and weight loss in some individuals, especially with diet and exercise.