Mounjaro (Tirzepatide) 5 mg Injection is a once-weekly subcutaneous treatment for type 2 diabetes mellitus in adults. It is a dual GIP and GLP-1 receptor agonist that mimics the action of two gut hormones, helping to regulate blood sugar levels and support weight management. The 5 mg dose is part of the dose-escalation regimen following the initial starting dose and may be maintained based on individual response and tolerability.

• Dual incretin-based therapy for effective blood sugar control

• Lowers both fasting and post-meal glucose levels

• Aids in weight reduction as a secondary benefit

• Convenient once-weekly injection improves patient adherence

• Can be used with other oral antidiabetic agents

• Administer once weekly, on the same day each week

• Inject subcutaneously into the abdomen, upper arm, or thigh

• Use a single-use prefilled pen for each dose

• Rotate injection sites to avoid irritation

• 5 mg is used after starting therapy with 2.5 mg and is typically continued for several weeks

• May be maintained or further escalated based on patient needs

• Only adjust the dose under healthcare supervision

• To be used along with diet and exercise

• Not for use in type 1 diabetes or diabetic ketoacidosis

• Contraindicated in patients with a personal or family history of medullary thyroid carcinoma or MEN 2

• Use cautiously in individuals with kidney or gastrointestinal conditions

• Not recommended for use during pregnancy or lactation unless advised by a physician

• Common side effects:

• Nausea

• Diarrhea

• Less common but serious effects:

• Pancreatitis

• Severe allergic reactions

• Gallbladder issues

• Hypoglycemia (when combined with other diabetes medications)

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• Vomiting

• Decreased appetite

• Indigestion or constipation

• Store in a refrigerator between 2°C and 8°C

• Do not freeze

• Can be kept at room temperature (up to 30°C) for up to 21 days

• Keep the pen in its original packaging to protect from light

• Store out of reach of children

Q1. Is 5 mg a starting dose for Mounjaro?
No, 5 mg is used after starting with the 2.5 mg dose to help the body adjust to the medication.

Q2. Can I take it with other diabetes medications?
Yes, it is commonly used alongside metformin or other antidiabetic drugs, based on doctor’s advice.

Q3. What if I miss a dose?
If a dose is missed, take it within 4 days. If more than 4 days have passed, skip that dose and continue as scheduled.

Q4. When will I see the benefits?
Most patients notice blood sugar improvement within a few weeks. Weight changes may become noticeable over time.