Oxitan Injection contains Oxaliplatin, a platinum-based chemotherapy drug primarily used in the treatment of advanced colorectal cancer. It is often combined with other anti-cancer agents like 5-fluorouracil (5-FU) and leucovorin in regimens such as FOLFOX. Oxaliplatin works by interfering with DNA replication in cancer cells, leading to their destruction and preventing the spread of cancer.

• Effective in the treatment of metastatic and advanced colorectal cancer

• Often used as part of combination chemotherapy regimens

• Delays disease progression and improves survival outcomes

• May be used in adjuvant therapy after surgical removal of tumors

• Administered under professional supervision in oncology centers

• Administered as an intravenous infusion by a trained healthcare provider

• Typically infused over 2 to 6 hours, depending on protocol

• Used in combination with other chemotherapy drugs

• Dosage cycles are usually repeated every 2 or 3 weeks

• Ensure adequate hydration and antiemetic support during treatment

• Active Ingredient: Oxaliplatin

• Formulation: 25 ml vial (concentration and total mg vary – confirm before use)

• Dosage is based on body surface area (BSA)

• Common regimen: 85 mg/m² every 2 weeks

• Adjust dose for renal impairment or toxicity

• Contraindicated in patients with known hypersensitivity to platinum compounds

• Use caution in patients with renal or hepatic dysfunction

• Not recommended during pregnancy or breastfeeding

• Patients should avoid exposure to cold temperatures after infusion

• Regular monitoring of CBC, liver, and kidney function is required

• Common Side Effects:

• Nausea and vomiting

• Peripheral neuropathy (tingling or numbness in extremities)

• Diarrhea

• Fatigue

• Serious Side Effects:

• Severe allergic reactions

• Pulmonary fibrosis

• Liver enzyme abnormalities

• Neutropenia with risk of infection

• Report any unusual symptoms such as difficulty breathing, chest tightness, or signs of infection immediately.

• Anemia and low white blood cell counts

• Store at 2°C to 8°C (refrigerated); do not freeze

• Keep the vial in the outer carton to protect from light

• Use diluted solution within 24 hours when stored at room temperature or 48 hours if refrigerated

• Keep out of reach of children

Q1. What is Oxitan used for?
A: Oxitan is used to treat colorectal cancer, typically in advanced stages or following surgery.

Q2. Can Oxitan be used alone?
A: It is most effective when used in combination with other chemotherapy agents like 5-FU.

Q3. Is hair loss a side effect of Oxitan?
A: Hair loss is uncommon with Oxaliplatin, but fatigue and neuropathy are more typical.

Q4. How is neuropathy managed during treatment?
A: Patients are advised to avoid cold exposure and may receive dose adjustments if symptoms worsen.

Q5. Can I eat normally during treatment?
A: A balanced diet is recommended, but discuss dietary restrictions with your oncologist or nutritionist.