Ozempic 1 mg is a once-weekly injectable medication containing Semaglutide, a GLP-1 receptor agonist designed to help manage blood sugar levels in adults with type 2 diabetes mellitus. It is used as a maintenance dose following initial titration and offers enhanced glycemic control for patients who require more than the standard 0.5 mg dose.

Ozempic not only improves HbA1c and fasting glucose levels but also promotes weight loss and supports cardiovascular health in patients with high-risk profiles.

• Superior reduction in HbA1c compared to lower doses

• Helps control both fasting and postprandial blood glucose

• Supports weight management by reducing appetite

• Proven to lower risk of cardiovascular events in type 2 diabetes

• Only once-weekly injection for patient convenience

• Administer 1 mg once weekly, via subcutaneous injection

• Inject in the abdomen, thigh, or upper arm

• Use on the same day each week, with or without food

• Do not mix with insulin or inject into a vein or muscle

• Rotate injection sites weekly to avoid skin irritation

• Typical dose progression:
  🔹 Start: 0.25 mg/week (4 weeks)
  🔹 Step up: 0.5 mg/week (at least 4 weeks)
  🔹 Maintenance: 1 mg/week

• Supplied in multi-dose pens

• Each 1 mg pen delivers 4 weekly doses (1-month supply)

• Not for use in type 1 diabetes or for treating diabetic ketoacidosis

• Contraindicated in patients with personal/family history of MTC or MEN 2 syndrome

• Caution in patients with pancreatitis, kidney disease, or severe GI issues

• Do not share the pen with others to avoid cross-contamination

• Disclose all medications to your doctor, especially insulin or oral hypoglycemics

• Common: Nausea, vomiting, diarrhea, stomach pain, constipation, reduced appetite

• Less Common: Fatigue, indigestion, bloating

• Serious: Pancreatitis, vision changes, allergic reactions, gallbladder problems

• Boxed Warning: Risk of thyroid C-cell tumors—monitor symptoms like neck swelling, hoarseness, or difficulty swallowing

• Unopened: Store in refrigerator (2°C to 8°C); do not freeze

• In use: Can be stored at room temperature (up to 30°C) for up to 56 days

• Always replace cap and store away from heat/light

• Keep out of reach of children

Q1. Who should use Ozempic 1 mg?
Patients who have not achieved target blood sugar levels with 0.5 mg weekly, or who need more robust glycemic control.

Q2. Does Ozempic 1 mg cause more side effects than lower doses?
Nausea and GI effects may be more common initially, but usually lessen with time. Gradual dose escalation helps reduce this risk.

Q3. Can I take Ozempic with metformin or insulin?
Yes, but close medical supervision is needed to adjust doses and prevent low blood sugar.

Q4. Can Ozempic help with weight loss?
Yes, weight loss is a significant benefit, and Ozempic 1 mg may offer more noticeable results compared to lower doses.