Pioglit MF Tablets 15 mg combine two antidiabetic agents—Pioglitazone (15 mg) and Metformin—designed to effectively manage type 2 diabetes mellitus in adults. This fixed-dose combination works through complementary mechanisms: Metformin reduces glucose production in the liver and improves insulin sensitivity, while Pioglitazone enhances glucose uptake in muscle and fat tissues. Together, they offer better glycemic control than either component alone.

• Dual action on insulin sensitivity and glucose production

• Helps lower both fasting and postprandial blood glucose levels

• Reduces HbA1c over time

• Suitable for patients who do not achieve control with monotherapy

• Lower risk of hypoglycemia compared to sulfonylureas

• Take one tablet daily, usually with meals to reduce gastrointestinal side effects

• Swallow the tablet whole with a glass of water

• Follow your doctor’s instructions regarding dosage and frequency

• Continue with prescribed diet and physical activity for optimal results

• Typical dose: Pioglitazone 15 mg + Metformin (strength varies) once or twice daily, based on the Metformin content

• Dosage may be adjusted by your physician depending on blood glucose response

• Not suitable for use in type 1 diabetes or diabetic ketoacidosis

• Blood sugar and kidney function should be monitored regularly

• Not recommended in patients with severe renal or hepatic impairment, heart failure, or bladder cancer

• May cause fluid retention, especially in patients with cardiac conditions

• Avoid excessive alcohol consumption

• Not advised during pregnancy or breastfeeding unless specifically prescribed

• Inform your doctor of any history of lactic acidosis

• Common side effects include:

• Gastrointestinal discomfort (nausea, diarrhea, bloating)

• Weight gain or edema

• Seek immediate medical help if you experience:

• Shortness of breath

• Rapid weight gain

• Unusual muscle pain or weakness

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• Headache or fatigue

• Risk of lactic acidosis (rare but serious)

• Store at room temperature (below 30°C)

• Protect from moisture, heat, and direct sunlight

• Keep tablets in their original packaging

• Keep out of reach of children

Q1. What is Pioglit MF used for?
It is prescribed to manage type 2 diabetes in adults when diet, exercise, and monotherapy do not provide sufficient glycemic control.

Q2. Can Pioglit MF cause low blood sugar?
It has a low risk of hypoglycemia when used alone, but the risk may increase if combined with insulin or sulfonylureas.

Q3. How soon can I see results with this medicine?
Blood sugar levels typically improve within 1 to 2 weeks, but full benefits on HbA1c may take several weeks to months.

Q4. Can I stop taking this if my blood sugar normalizes?
No. Always follow your doctor’s advice. Stopping treatment suddenly can lead to a rebound in blood sugar levels.