Pregabalin 150 mg is an anticonvulsant and neuropathic pain relief medication used to treat a variety of conditions, including nerve pain, seizures, and anxiety disorders. It is often prescribed for diabetic neuropathy, fibromyalgia, and postherpetic neuralgia. Pregabalin works by stabilizing electrical activity in the brain and reducing the release of certain neurotransmitters involved in pain and anxiety.

Pregabalin is also used as an adjunctive treatment for partial-onset seizures and to alleviate generalized anxiety disorder (GAD).

• Provides effective pain relief from nerve-related conditions

• Reduces seizures when used alongside other anticonvulsant drugs

• Helps manage symptoms of generalized anxiety disorder (GAD)

• Relieves fibromyalgia pain and improves quality of life

• Works quickly and is well-tolerated with fewer side effects compared to older pain relievers

• Neuropathic pain due to conditions like diabetic neuropathy or postherpetic neuralgia

• Fibromyalgia – helps manage widespread pain

• Seizures – as an adjunctive therapy for partial-onset seizures

• Generalized Anxiety Disorder (GAD) – provides relief from anxiety symptoms

• Standard dose: 150 mg per day, which can be divided into 2 or 3 doses

• Your doctor may adjust the dose based on your response and condition.

• Starting dose: Typically begins at 75 mg twice a day, then adjusted as needed.

• Swallow the tablet whole with a glass of water. Do not crush or chew.

• Can be taken with or without food.

Always follow your doctor's instructions and dosage recommendations.

• Use with caution in patients with a history of kidney disease or heart failure

• May cause dizziness or drowsiness—avoid activities requiring alertness until you understand how the medication affects you

• Pregabalin can increase the risk of suicidal thoughts—monitor mood changes

• Do not suddenly stop taking Pregabalin without consulting your doctor, as it may lead to withdrawal symptoms

• Not recommended during pregnancy or breastfeeding, unless prescribed by a healthcare provider

• Common: Dizziness, drowsiness, dry mouth, weight gain, blurred vision

• Occasional: Swelling in the hands or feet, difficulty concentrating, trouble with memory

• Rare but Serious: Mood changes, suicidal thoughts, severe allergic reactions, muscle pain or tenderness (can indicate a serious side effect)

Seek immediate medical attention if you experience severe side effects or signs of an allergic reaction.

• Alcohol: Can enhance the sedative effects of Pregabalin, increasing the risk of drowsiness or dizziness

• CNS depressants: Combining with benzodiazepines, opioids, or other sedatives can lead to severe drowsiness or breathing problems

• Other medications: Always inform your doctor of other medications, particularly for seizure control, anxiety, or diabetes treatments.

• Store in a cool, dry place away from moisture, heat, and sunlight

• Keep at room temperature (15–30°C)

• Keep out of reach of children and pets

Q1. How does Pregabalin work?
Pregabalin works by binding to calcium channels in the brain, reducing the release of excitatory neurotransmitters and stabilizing electrical activity, which helps to manage nerve pain and prevent seizures.

Q2. Can I use Pregabalin for anxiety?
Yes, Pregabalin is approved for the treatment of generalized anxiety disorder (GAD) and can help alleviate anxiety symptoms.

Q3. Will Pregabalin make me sleepy?
Yes, drowsiness is a common side effect, especially during the first few days of treatment. It is important to avoid driving or operating heavy machinery until you know how the drug affects you.

Q4. Can I take Pregabalin for fibromyalgia?
Yes, Pregabalin is commonly prescribed for fibromyalgia pain and has been shown to reduce symptoms and improve the overall quality of life for patients.