Pregabalin 300 mg is an anticonvulsant and pain-relieving medication primarily used for the management of neuropathic pain, seizures, and generalized anxiety disorder (GAD). Pregabalin works by stabilizing nerve activity and reducing neurotransmitter release, helping to relieve conditions associated with nerve damage or hyperactivity. It is commonly prescribed for diabetic neuropathy, postherpetic neuralgia, and fibromyalgia.

Pregabalin also serves as an adjunct therapy for partial-onset seizures and provides effective relief from anxiety-related disorders.

• Neuropathic pain relief associated with diabetic neuropathy, postherpetic neuralgia, and fibromyalgia

• Reduces the frequency of partial-onset seizures in combination with other anticonvulsants

• Provides relief from symptoms of generalized anxiety disorder (GAD)

• Well-tolerated and effective in managing nerve pain and muscle pain

• Helps alleviate discomfort and improves quality of life

• Neuropathic pain due to diabetic neuropathy or postherpetic neuralgia

• Fibromyalgia – relieves widespread muscle pain

• Partial-onset seizures – as an adjunctive treatment

• Generalized Anxiety Disorder (GAD) – provides anxiety relief and enhances emotional well-being

• Starting dose: Typically 150 mg per day, divided into 2 or 3 doses

• The dose may be adjusted based on the condition being treated, up to a maximum of 600 mg/day

• Pregabalin can be taken with or without food

• Do not chew, crush, or break the tablet—swallow whole with water

Always follow your doctor's prescribed dosage and instructions.

• Kidney function: Pregabalin is primarily excreted by the kidneys; use with caution in those with renal impairment

• Drowsiness and dizziness: Can impair your ability to perform tasks requiring focus, such as driving

• Suicidal thoughts: Increased risk—monitor for mood changes, especially at the start of therapy

• Withdrawal: Do not suddenly stop taking Pregabalin—gradual dose reduction is recommended to avoid withdrawal symptoms

• Pregnancy and breastfeeding: Consult a doctor before use during pregnancy or breastfeeding

• Common: Drowsiness, dizziness, dry mouth, blurred vision, weight gain, and trouble concentrating

• Occasional: Swelling in the hands, feet, or legs, memory issues, or balance problems

• Serious but Rare: Skin rash, unusual mood swings, allergic reactions, and muscle tenderness (can be indicative of a severe side effect)

🛑 Seek immediate medical attention if you experience any severe side effects or signs of an allergic reaction.

• CNS depressants: Combining with opioids, benzodiazepines, or alcohol may enhance sedative effects, leading to increased drowsiness and respiratory depression

• Other anticonvulsants: Consult your healthcare provider before combining with other seizure medications

• Diabetes medications: Adjustments may be necessary, as Pregabalin can affect blood sugar levels

• Store in a cool, dry place away from direct light and moisture

• Keep at room temperature (15–30°C)

• Keep out of reach of children and pets

Q1. What is Pregabalin used for?
Pregabalin is primarily used for treating neuropathic pain, seizures, and generalized anxiety disorder. It is also prescribed for conditions like fibromyalgia and postherpetic neuralgia.

Q2. How does Pregabalin work for pain relief?
Pregabalin reduces the release of neurotransmitters involved in pain transmission, thus modulating nerve activity and providing pain relief, especially for nerve-related pain.

Q3. Can Pregabalin be used to treat anxiety?
Yes, Pregabalin is approved for the treatment of generalized anxiety disorder (GAD) and helps alleviate symptoms such as nervousness, restlessness, and excessive worry.

Q4. Are there any serious side effects to watch out for?
Although rare, serious side effects include muscle tenderness or pain, skin rash, and changes in mood or behavior. It's important to report any unusual symptoms to your healthcare provider immediately.

Q5. Is Pregabalin addictive?
Pregabalin has a low potential for abuse when taken as prescribed. However, misuse can lead to dependence, so it should only be used under medical supervision.