Qtern Tablets combine Saxagliptin (5 mg), a DPP-4 inhibitor, and Dapagliflozin (10 mg), an SGLT2 inhibitor, to effectively manage type 2 diabetes mellitus in adults. This dual-action therapy helps improve glycemic control by increasing insulin secretion, reducing glucose reabsorption in the kidneys, and enhancing urinary glucose excretion. Qtern is suitable for patients who need additional control beyond monotherapy or metformin.

• Provides complementary mechanisms to lower blood glucose levels

• Aids in reducing HbA1c in patients with type 2 diabetes

• Promotes modest weight loss and blood pressure reduction

• Low risk of hypoglycemia when used without insulin or sulfonylureas

• Convenient once-daily oral tablet with two agents in one pill

• Take one tablet once daily, preferably in the morning

• Can be taken with or without food

• Swallow the tablet whole with water

• Follow the prescribed regimen from your healthcare provider

• Fixed-dose combination: Saxagliptin 5 mg + Dapagliflozin 10 mg

• Not recommended in patients with severe renal impairment (eGFR <45 mL/min/1.73 m²)

• Dose adjustments may be required based on kidney function or concurrent therapy

• Do not split or crush the tablet

• Not for use in type 1 diabetes or diabetic ketoacidosis

• Caution in patients with kidney or liver disease, urinary tract infections, or a history of genital infections

• Monitor renal function and blood sugar levels regularly

• Not recommended during pregnancy or breastfeeding

• Stay hydrated to reduce the risk of dehydration and low blood pressure

• Common side effects include:

• Urinary tract infections

• Genital infections (fungal)

• Rare but serious side effects:

• Ketoacidosis

• Pancreatitis

• Hypersensitivity reactions

• Acute kidney injury

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• Increased urination

• Headache

• Nasopharyngitis

• Store at room temperature (below 30°C)

• Protect from moisture and heat

• Keep in original packaging

• Keep out of reach of children

Q1. What is Qtern used for?
Qtern is used to improve blood sugar control in adults with type 2 diabetes, especially when metformin alone is insufficient.

Q2. Can Qtern cause low blood sugar?
The risk is low when used alone, but it may increase when combined with insulin or sulfonylureas.

Q3. Is Qtern suitable for patients with kidney problems?
It is not recommended for those with severe renal impairment. Renal function should be assessed before and during treatment.

Q4. Can Qtern help with weight loss?
Yes, Dapagliflozin may contribute to modest weight loss as it promotes glucose excretion through urine.