Resihance 40 mg contains Regorafenib, an oral multikinase inhibitor used in the treatment of certain types of advanced cancers. It targets several enzymes involved in tumor growth, angiogenesis (formation of blood vessels), and the tumor microenvironment. Regorafenib is commonly prescribed for metastatic colorectal cancer, advanced gastrointestinal stromal tumors (GIST), and hepatocellular carcinoma (HCC) when other therapies have failed.

• Inhibits cancer cell proliferation and angiogenesis

• Approved for metastatic colorectal cancer (mCRC), GIST, and liver cancer (HCC)

• Provides a treatment option for patients with limited response to standard chemotherapy

• Oral formulation for convenient administration

• Demonstrates survival benefit in advanced cancer patients

• Take Resihance 40 mg once daily as directed by your oncologist

• Usually taken for 21 days followed by a 7-day rest period (28-day cycle)

• Swallow the tablet whole with water after a low-fat meal

• Follow the schedule exactly as prescribed; do not skip or double doses

• Strength: 40 mg Regorafenib per tablet

• Recommended starting dose: 160 mg once daily (four 40 mg tablets)

• Dosing schedule: 3 weeks on treatment, 1 week off

• Dose adjustments may be necessary based on side effects and lab results

• Always consult your physician before making any changes to your dose

• Not recommended during pregnancy or breastfeeding

• Use effective contraception during and after treatment (up to 2 months)

• Monitor liver function, blood pressure, and signs of bleeding

• Inform your doctor if you have heart problems, liver disease, or recent surgery

• Avoid grapefruit juice, which may interfere with drug metabolism

Common Side Effects:

• Fatigue

• Loss of appetite

• Hand-foot skin reaction (palmar-plantar erythrodysesthesia)

• Diarrhea

• High blood pressure

Serious Side Effects:

• Liver toxicity (elevated liver enzymes)

• Severe bleeding

• Heart-related issues like myocardial infarction

• Risk of infection

• Gastrointestinal perforation (rare)

• Store at 20°C to 25°C (68°F to 77°F)

• Keep away from moisture, heat, and light

• Store in the original container and close tightly after each use

• Keep out of reach of children and pets

Q1. What is Resihance used for?
A: Resihance is used to treat advanced or metastatic colorectal cancer, GIST, and hepatocellular carcinoma after prior treatment failure.

Q2. Can I take Resihance with food?
A: Yes, it should be taken after a low-fat meal to optimize absorption and reduce gastrointestinal side effects.

Q3. How is the treatment cycle structured?
A: Typically, it is taken daily for 21 days, followed by 7 days off (a 28-day cycle).

Q4. What monitoring is required?
A: Regular liver function tests, blood pressure checks, and assessments for bleeding or heart issues are important during treatment.

Q5. Can Resihance be used long-term?
A: Treatment duration is based on response and tolerance. Your oncologist will determine the most appropriate length of therapy.