Syncapone 150 mg Tablets are a triple-combination formulation containing Levodopa, Carbidopa, and Entacapone, used in the treatment of Parkinson’s disease. This formulation helps restore dopamine levels in the brain, improving motor function and reducing symptoms such as tremors, rigidity, and bradykinesia. Syncapone enhances the effectiveness of Levodopa therapy and helps manage "wearing-off" symptoms in patients undergoing long-term Parkinson’s treatment.

• Combines Levodopa (150 mg), Carbidopa, and Entacapone in one tablet

• Helps manage motor fluctuations in Parkinson’s disease

• Improves Levodopa efficacy and extends its duration of action

• Reduces “off” periods and enhances movement control

• Supports better symptom management in advanced Parkinson’s patients

Take the tablet orally as prescribed by your physician, usually with or without food. Dosing is typically individualized based on disease progression and prior Levodopa treatment. Do not break or crush the tablet unless advised.

• Strength: Levodopa 150 mg + Carbidopa + Entacapone

• Route: Oral

• Frequency: As directed by the treating neurologist

• Used for patients already stabilized on Levodopa/Carbidopa therapy

• Not to be used in untreated Parkinson’s patients

• Avoid abrupt discontinuation; tapering may be necessary

• Use with caution in patients with cardiovascular, hepatic, or psychiatric conditions

• May interact with MAO inhibitors or other dopaminergic drugs

• Avoid activities requiring alertness until drug effects are known

Common side effects may include:

• Nausea

• Diarrhea

• Dizziness

• Dyskinesia (involuntary movements)

• Sleep disturbances

Seek immediate medical attention for hallucinations, sudden sleep attacks, or signs of liver dysfunction.

• Store at room temperature (15°C–30°C) in a dry place

• Keep away from heat, moisture, and direct light

• Store out of reach of children

Q1: What is Syncapone used for?
Syncapone is used to manage motor fluctuations in Parkinson’s disease, especially in patients already receiving Levodopa/Carbidopa.

Q2: How does Entacapone help?
Entacapone inhibits COMT, an enzyme that breaks down Levodopa, thereby extending its action and reducing "off" time.

Q3: Can Syncapone be used as initial therapy?
No. It is generally prescribed for patients who are already stabilized on Levodopa/Carbidopa.

Q4: Does Syncapone cure Parkinson’s disease?
No. It helps control symptoms but does not cure the disease.

Q5: Are there dietary restrictions while using Syncapone?
Avoid high-protein meals close to dosing, as they may interfere with Levodopa absorption.