Trulicity Pre-Filled Pen 0.75 mg contains Dulaglutide, a long-acting GLP-1 receptor agonist indicated for the management of type 2 diabetes mellitus in adults. It works by stimulating insulin release, decreasing glucagon secretion, and slowing gastric emptying to help regulate blood sugar levels. This once-weekly injection is often used as an initial dose to assess tolerability before increasing to higher strengths like 1.5 mg.

• Helps control blood sugar levels in type 2 diabetes

• Supports cardiovascular health in at-risk diabetic patients

• Once-weekly dosing improves adherence

• May assist with gradual weight reduction

• Minimal risk of hypoglycemia when used without insulin or sulfonylureas

• Administer subcutaneously once a week in the abdomen, thigh, or upper arm

• Can be injected any time of the day, with or without food

• Use a new pre-filled pen for each dose

• Rotate injection sites to prevent skin irritation

• Follow your doctor’s instructions for initiating treatment and dose adjustments

• Typical starting dose: 0.75 mg once weekly

• Your doctor may increase the dose to 1.5 mg or higher after assessing response and tolerability

• Do not inject more than once in a 7-day period

• If a dose is missed, administer within 3 days or skip until the next scheduled dose

• Not indicated for type 1 diabetes or diabetic ketoacidosis

• Use with caution in individuals with a history of pancreatitis, kidney problems, or gastrointestinal disorders

• Contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)

• Inform your doctor if pregnant, breastfeeding, or planning surgery

• Avoid alcohol and stay hydrated to minimize GI side effects

• Common side effects may include:

• Nausea

• Vomiting

• Serious but rare side effects:

• Pancreatitis (sharp abdominal pain radiating to the back)

• Kidney impairment

• Severe allergic reactions (rash, difficulty breathing, swelling)

• Thyroid tumors (rare; monitor for neck lumps, hoarseness, or trouble swallowing)

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• Diarrhea

• Abdominal discomfort

• Loss of appetite

• Store unused pens in a refrigerator (2°C to 8°C)

• Do not freeze; discard if frozen

• After opening or removing from refrigeration, may be kept at room temperature (below 30°C) for up to 14 days

• Protect from direct light and keep in original packaging

• Keep out of reach of children

Q1. What is Trulicity 0.75 mg used for?
It is used to initiate blood sugar control in adults with type 2 diabetes and may be the starting dose before titration.

Q2. How do I administer Trulicity?
It is injected once weekly under the skin using a pre-filled pen. Follow the instructions provided by your doctor or pharmacist.

Q3. Can I eat before or after using Trulicity?
Yes, Trulicity can be taken with or without meals.

Q4. Does Trulicity cause low blood sugar?
Not typically when used alone, but the risk increases when used with insulin or sulfonylureas.