Ursodiol, or ursodeoxycholic acid, is a bile acid used to treat conditions related to the liver and gallbladder. It is particularly effective in managing primary biliary cirrhosis (PBC), gallstones, and other liver disorders. The 150 mg tablet is a suitable dosage for patients requiring a lower dose, often prescribed for gallstone prevention, or to assist with liver disease management.

• Ursodiol 150 mg: Ideal for patients needing a lower dosage to manage liver and gallbladder conditions.

• Effective for liver and gallbladder diseases: Helps treat primary biliary cirrhosis (PBC) and gallstones.

• Supports liver health: Works to dissolve cholesterol-based gallstones and protect liver cells from toxic bile acids.

• FDA-approved and well-established: Known for its efficacy and safety over decades of use in clinical practice.

Ursodiol 150 mg tablets are typically prescribed for the following conditions:

• Primary biliary cirrhosis (PBC): To reduce liver damage and improve liver function.

• Gallstones: To dissolve cholesterol-based gallstones and prevent new ones from forming.

• Cholestasis: To improve bile flow and reduce liver damage due to impaired bile secretion.

• Liver disease: For the protection and maintenance of liver health in chronic conditions.

Ursodiol works by reducing cholesterol production in the liver and promoting bile flow, which helps to prevent the formation of cholesterol-based gallstones. It also helps to dissolve existing stones, making them easier to pass. Ursodiol reduces the amount of toxic bile acids in the liver, protecting the liver cells and improving liver function.

• Dosage: The typical starting dose for Ursodiol 150 mg is one tablet taken once or twice daily, depending on the specific condition being treated.

• Dosage adjustment: Your healthcare provider may adjust the dose based on your response to the medication.

• Administration: Take the tablet with a full glass of water. Swallow it whole, and do not crush or chew it.

• Consistency: It’s important to take Ursodiol at the same time every day for optimal effectiveness.

• Pregnancy and breastfeeding: Consult your doctor before taking Ursodiol if you are pregnant or breastfeeding.

• Liver conditions: Notify your doctor if you have existing liver conditions or a history of liver disease, as Ursodiol may need to be monitored closely.

• Drug interactions: Ursodiol may interact with other medications, including bile acid sequestrants and antacids, so make sure to inform your healthcare provider of all the medications you are currently taking.

• Alcohol: Limit alcohol consumption while taking Ursodiol, as it can affect liver health.

Although Ursodiol is generally well-tolerated, some people may experience side effects, including:

• Diarrhea

• Constipation

• Stomach cramps or discomfort

• Nausea or indigestion

• Headaches

In rare cases, serious side effects may occur, such as yellowing of the skin or eyes, dark urine, or severe abdominal pain. If you notice any of these symptoms, seek medical attention immediately.

• Store at room temperature (15°C to 30°C), away from moisture and heat.

• Keep the medication in a dry place, out of direct sunlight.

• Keep out of reach of children.

• Do not use the medication after the expiration date.

Q1: How long will it take for Ursodiol to start working?
It may take several weeks to months to see the full benefits of Ursodiol, particularly in the treatment of liver diseases or gallstones. Continue taking the medication as prescribed, and your doctor will monitor your progress.

Q2: Can I take Ursodiol for a long time?
Yes, Ursodiol is generally safe for long-term use under a healthcare provider’s guidance, especially for chronic conditions like primary biliary cirrhosis. Regular check-ups are advised.

Q3: Can Ursodiol interact with other medications?
Yes, Ursodiol may interact with other medications, particularly those affecting bile acid metabolism. Inform your doctor of all other medications you're taking, including over-the-counter drugs and supplements.

Q4: Are there any dietary restrictions while taking Ursodiol?
There are no specific dietary restrictions with Ursodiol. However, maintaining a healthy diet and avoiding excessive alcohol can help support your liver health.