Xafinact 50 mg Tablets contain Safinamide, a selective monoamine oxidase-B (MAO-B) inhibitor used as an adjunct treatment for Parkinson’s disease. It is primarily prescribed alongside levodopa and other Parkinson’s medications to manage "off" episodes—periods when symptoms return between medication doses. Safinamide works by increasing dopamine levels in the brain and modulating glutamate release, helping improve motor control and reduce stiffness, tremors, and slowness of movement.

• Enhances motor function in patients with Parkinson’s disease

• Reduces "off" time in patients receiving levodopa therapy

• Supports smoother, more consistent symptom control

• Once-daily dosing for improved patient compliance

• Well-tolerated with a favorable safety profile

Take Xafinact 50 mg Tablets exactly as prescribed by your neurologist. Swallow the tablet whole with a glass of water, with or without food. It is typically taken once daily at the same time. Do not crush, split, or chew the tablet. Continue taking it even if you feel well, unless directed otherwise by your doctor.

• The usual starting dose is 50 mg once daily

• Based on clinical response, your doctor may increase the dose to 100 mg after two weeks

• Always follow your doctor’s instructions and do not adjust the dose on your own

• Xafinact is used as an add-on therapy with a stable dose of levodopa

• Not recommended for patients with severe liver impairment

• Inform your doctor if you have a history of bipolar disorder, psychosis, or eye disorders

• Avoid taking with other MAO inhibitors or drugs that increase serotonin levels (e.g., SSRIs, SNRIs) without medical advice

• May cause dizziness or drowsiness—use caution when driving or operating machinery

• Alcohol should be avoided during treatment

Common side effects include:

• Insomnia

• Headache

• Nausea

• Fall-related injuries

• Increased blood pressure
  Less common but serious effects:

• Hallucinations or confusion

• Impulse control disorders (e.g., compulsive behavior)

• Serotonin syndrome when combined with certain medications

Seek immediate medical help if you experience chest pain, severe agitation, or signs of allergic reaction.

• Store at room temperature (15°C–30°C / 59°F–86°F)

• Keep away from moisture, heat, and direct sunlight

• Store in the original blister packaging

• Keep out of reach of children

• Do not use the tablet past its expiration date

Q: What is Xafinact 50 mg used for?
A: It is used as an adjunct treatment in adults with Parkinson’s disease to reduce "off" episodes and enhance motor function.

Q: Can I take Xafinact alone for Parkinson’s?
A: No. It is approved for use with a stable dose of levodopa, with or without other Parkinson’s medications.

Q: How soon will I notice improvement in symptoms?
A: Some patients may notice improvement within a few weeks, but full benefits may take longer. Regular use as prescribed is important.

Q: Is Xafinact habit-forming?
A: No, Safinamide is not habit-forming, but it must be used under medical supervision.